As the title says, the main character is Satan's daughter. Yukina, a fourteen year old girl studying at an academy for gifted students and world nobles, is the main victim of bullies. Not only the students hate her, teachers, adults and the citizens are all disgusted by her. But one day get grandmother's death is framed to be because of her. She flees to the New World where she becomes part of the 'Twelve Supernovas'